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MailUp automatically moves some users to unsubscribed anyway, so to guarantee the best deliverability rates possible, and avoid antispam filters. In particular, the system unsubscribes the users described below. Afterwards, actions such as notices, post-operations or exports via batch ftp mode to external systems are always possible. 

Users clicking the "spam" button (abuse reports)

Most email clients like Gmail or Yahoo! - although not all of them - provide a "Spam" or "Junk" button. Clicking this button triggers a notice to MailUp, called "Feedback Loop" (FBL). In order to stop sending messages to these recipients, so to keep a high level of reputation and maximize deliverabilitythey are automatically moved to unsubscribers. It is possible to filter these recipients using the dropdown menu "Unsubscribed from" at the page Recipients > Unsubscribed, choosing "because misuse has been reported" (see image below). The report can also be exported.

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Page that shows unsubscribers, sorted by reason. 

 

Users clicking the unsubscribe button provided by email clients

Some web email clients have another button besides "Spam" or "Junk", usually called "Unsubscribe". 

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Users with invalid email address

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C'è una particolare classe di errori definita Hard Bounce (tipicamente con errore Image Added

There is a peculiar kind of error called Hard Bounce (usually with error code 550 5.1.1) che corrisponde a indirizzi email non esistenti (errore which refers to non existing email addresses (mailbox not found, no such user here…). Queste caselle sono sicuramente errate, quindi già dopo un primo errore vengono automaticamente disiscritte (come sempre isolabili dalle altre). La rimozione tempestiva degli Hard Bounce dagli elenchi di invio è fondamentale per arrivare ad un elevata reputazione (solo gli spammer hanno liste sporche), evitando così di essere bloccati dai sistemi antispam. 
Fare riferimento a http://assistenza.mailup.it/KB/a97/gestione-dei-bounce-e-pulizia-delle-email-errate.aspxThese addresses are undoubtedly invalid, so they are automatically unsubscribed after returning the very first error and they can be filtered at the page Recipients > Unsubscribed. The quick removal of Hard Bounces from databases is paramount to maintain a high level of reputation, and to avoid having messages blocked by antispam systems.
For further information see the page http://support.mailup.com/KB/a263/how-managing-bounces-affects-reputation-and-deliverability.aspx?KBSearchID=3375